Isatisine A
Basics
Category
Indolics & indole alkaloid derivatives
IUPAC-name
(2R,3R,3aR,10aS,10bS)-3,3a-dihydroxy-2-(hydroxymethyl)-10a-(1H-indol-3-yl)-3,3a,10a,10b-tetrahydro-4H-furo[2',3':3,4]pyrrolo[1,2-a]indole-4,10(2H)-dione
Formula
No formula stored
Exact mass
406.11649 g/mol
Molecular weight
No weights stored
Structure
Sources
In summary, the chemical isatisine A has been analyzed from following sources:
Note that an analysis result in the database may indicate either presence or lack thereof of a chemical in an analyzed sample.
References
- J. Liu, Z. Jiag, R. Wang, Y. Zheng, J. Chen, X. Zhang, and Y. Ma, "Isatisine A, a novel alkaloid with an unprecedented skeleton from leaves of Isatis indigotina.," Organic Letters , vol. 9 , no. 21 , pp. 4127–4129 , DOI: 10.1021/ol701540y .
Analysis results
Analysis result 1
| Detection technique | Values | Units |
|---|---|---|
| [M⁻ H]⁻ | 405 | m/z |
| MS²⁻ |
311
325 339 353 |
m/z |
STD
False
TLC
True
UV/Vis detector description
UV
Mass spectrometer description
HR-ESI-MS, FAB-MS
Organism
Isatis indigotina
wild
dried, powdered
Collection dates
2004-11
Sample note
The samples of Isatis indigotina were identified by professor Ya-qiu Zhou of Anhui College of Traditional Chinese Medicine (voucher No. 2004-11-5).NOTE. There are conflicting views on the taxonomy of I. tinctoria (European woad) and I. indigotica (Chinese woad). I. indigotina was described for the first time by Fortune in 1846, and initially considered as a distinct species. Afterward, some taxonomists have classified it as a variety of I. tinctoria. Nowadays, I. indigotina is considered as a synonym of I. tinctoria [e.g. The Plant List, IPNI (International Plant Name Index), Tropicos]. (Speranzo et al. 2020). In this database, we use the names similarly as the authors.
Drying methods
air-dried
Extraction solvents
80 % ethanol
Extraction repeats
3
Extraction time
2 h
Extract drying method
concentrated under a vacuum
Detection note
FAB-MS m/z 405 --> 339 (100), 325 (90), 311 (40), 353 (10)
References
J. Liu, Z. Jiag, R. Wang, Y. Zheng, J. Chen, X. Zhang, and Y. Ma, "Isatisine A, a novel alkaloid with an unprecedented skeleton from leaves of Isatis indigotina.," Organic Letters , vol. 9 , no. 21 , pp. 4127–4129 , DOI: 10.1021/ol701540y .