Chemical fact sheet: 3,5,4'-trihydroxy-6,7-methylenedioxyflavone

3,5,4'-trihydroxy-6,7-methylenedioxyflavone

Basics

Category
Flavone and flavonol derivatives
IUPAC-name
7,9-dihydroxy-6-(4-hydroxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromen-8-one
Formula
No formula stored
Exact mass
314.04270 g/mol
Molecular weight
No weights stored
Structure
Chemical structure of 3,5,4'-trihydroxy-6,7-methylenedioxyflavone
Figure 1.1: Chemical structure of 3,5,4'-trihydroxy-6,7-methylenedioxyflavone

Sources

In summary, the chemical 3,5,4'-trihydroxy-6,7-methylenedioxyflavone has been analyzed from following sources:

Polygonum tinctorium
1st 2nd

Note that an analysis result in the database may indicate either presence or lack thereof of a chemical in an analyzed sample.

References

  1. H. Kimura, T. Ishihara, M. Michida, S. Ogawa, T. Akihiro, and K. Yokota, "Identification and quantitative analysis of polyphenolic compounds from the indigo plant (Polygonum tinctorium Lour).," Natural Product Research , vol. 28 , no. 7 , pp. 492–495 , DOI: 10.1080/14786419.2013.871719 .
  2. H. Kimura, S. Tokuyama, T. Ishihara, S. Ogawa, and K. Yokota, "Identification of new flavonol O-glycosides from indigo (Polygonum tinctorium Lour) leaves and their inhibitory activity against 3-hydroxy-3-methylglutaryl-CoA reductase.," Journal of Pharmaceutical and Biomedical Analysis , vol. 108 , pp. 102–112 , DOI: 10.1016/j.jpba.2015.02.005 .

Analysis results

Analysis result 1

Detection technique Values Units
[M⁻ H]⁻ 313 m/z
STD
False
TLC
False
UV/Vis detector description
photodiode array (PDA)
Mass spectrometer description
UPLC-ESI/MS
Organism
Polygonum tinctorium
cultivated
ground into 5-mm pieces, fresh, ground
Collection dates
2012
Sample note
The species was confirmed by Professor Shuji Hamasaki et Shimane Prefectual College for Agriculture and Forestry (Ohda, Shimane, Japan). The voucher specimen (voucher number 12001) were deposited in the laboratory of the Department of Research and Development, Kotobuki Seika, Japan).
Extraction solvents
methanol
Extraction mass/volume-ratio
333.3 mg/mL
Extraction repeats
1
Extraction time
3 h
Extraction temperature
20±5 °C
Extract drying method
evaporation to dryness by a rotatory evaporator
Extract drying temperature
40 °C
Analysis solvents
50 % MeOH, 100 % MeOH
References

H. Kimura, T. Ishihara, M. Michida, S. Ogawa, T. Akihiro, and K. Yokota, "Identification and quantitative analysis of polyphenolic compounds from the indigo plant (Polygonum tinctorium Lour).," Natural Product Research , vol. 28 , no. 7 , pp. 492–495 , DOI: 10.1080/14786419.2013.871719 .

Analysis result 2

Detection technique Values Units
UV/Vis 241
273
354 		nm
[M⁻ H]⁻ 313.03000 m/z
STD
False
TLC
False
UV/Vis detector description
UV/Vis, UPLC-PDA
Mass spectrometer description
UPLC-ESI-TOF/MS
Organism
Polygonum tinctorium
cultivated
fresh, cut, cut into 5-mm squares
Sample note
The plants were cultivated from the seeds in a field of Sakaiminato, Tottori in Japan. The voucher specimen (No. 14001) has been deposited in the Department of Research and Development, Kotobuki Seika, Japan.
Extraction solvents
80 % methanol
Extraction mass/volume-ratio
20.9 mg/mL
Extraction repeats
1
Extraction time
2 h
Extraction temperature
70 °C
Extract drying method
evaporation to dryness
Extract drying temperature
40 °C
Analysis solvents
100 % MeOH
Detection note
light green capillary crystal
References

H. Kimura, S. Tokuyama, T. Ishihara, S. Ogawa, and K. Yokota, "Identification of new flavonol O-glycosides from indigo (Polygonum tinctorium Lour) leaves and their inhibitory activity against 3-hydroxy-3-methylglutaryl-CoA reductase.," Journal of Pharmaceutical and Biomedical Analysis , vol. 108 , pp. 102–112 , DOI: 10.1016/j.jpba.2015.02.005 .