Chemical fact sheet: Gniditrin

Gniditrin

Basics

Category
Diterpenoids
IUPAC-name
(2S,3aR,3bS,3cS,4aR,5S,5aS,8aR,8bR,9R,10R,10aS)-5,5a-dihydroxy-4a-(hydroxymethyl)-7,9-dimethyl-6-oxo-2-phenyl-10a-(prop-1-en-2-yl)-3a,3b,3c,4a,5,5a,8a,9,10,10a-decahydro-6H-2,8b-epoxyoxireno[2'',3'':6',7']azuleno[5',4':3,4]benzo[1,2-d][1,3]dioxol-10-yl (2E,4E,6E)-deca-2,4,6-trienoate
Formula
No formula stored
Exact mass
646.27780 g/mol
Molecular weight
646.70000 g/mol
Structure
Chemical structure of gniditrin
Figure 1.1: Chemical structure of gniditrin

Sources

In summary, the chemical gniditrin has been analyzed from following sources:

Daphne alpina  L.
1st
Daphne mezereum  L.
1st

Note that an analysis result in the database may indicate either presence or lack thereof of a chemical in an analyzed sample.

References

  1. C. Görick, and M. Melzig, "Gniditrin is the main diterpenoid constituent in the bark of Daphne mezereum L.," Pharmazie , vol. 68 , no. 7 , pp. 640–642 , DOI: 10.1692/ph.2013.6522 .

Analysis results

Analysis result 1

Detection technique Values Units
[M⁺ H]⁺ 647.28000 m/z
STD
False
TLC
False
UV/Vis detector description
Mass spectrometer description
ESI-TOF, HPLC-DAD-ESI-MS
Organism
Daphne mezereum  L.
powdered, dried, milled
Collection dates
2010
Sample note
The twigs of Daphne mezereum L. were collected and authenticated in the Botanical Garden Berlin in spring 2010. The fresh twigs were peeled and the bark was dried for 2 days at room temperature, then milled.
Drying methods
air-dried
Extraction solvents
96 % ethanol (v/v)
Extraction mass/volume-ratio
25 mg/mL
Extract drying method
evaporation under reduced pressure
Analysis solvents
100 % methanol
Detection note
Gniditrin was the main diterpene constituent in the bark of D. mezereum.
References

C. Görick, and M. Melzig, "Gniditrin is the main diterpenoid constituent in the bark of Daphne mezereum L.," Pharmazie , vol. 68 , no. 7 , pp. 640–642 , DOI: 10.1692/ph.2013.6522 .

Analysis result 2

Detection technique Values Units
[M⁺ H]⁺ 647.28000 m/z
STD
False
TLC
False
UV/Vis detector description
Mass spectrometer description
ESI-TOF, HPLC-DAD-ESI-MS
Organism
Daphne alpina  L.
powdered, dried, milled
Collection dates
2010
Sample note
The twigs of Daphne alpina L. were collected and authenticated in the Botanical Garden Berlin in spring 2010. The fresh twigs were peeled and the bark was dried for 2 days at room temperature, then milled.
Drying methods
air-dried
Extraction solvents
96 % ethanol (v/v)
Extraction mass/volume-ratio
25 mg/mL
Extract drying method
evaporation under reduced pressure
Analysis solvents
100 % methanol
Detection note
Gniditrin was the main diterpene constituent in the bark of D. alpina.
References

C. Görick, and M. Melzig, "Gniditrin is the main diterpenoid constituent in the bark of Daphne mezereum L.," Pharmazie , vol. 68 , no. 7 , pp. 640–642 , DOI: 10.1692/ph.2013.6522 .