Chemical fact sheet: Sennoside A

Sennoside A

Basics

Category
Anthrone derivatives
IUPAC-name
(9R,9'R)-4,4'-dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid
Formula
No formula stored
Exact mass
862.19564 g/mol
Molecular weight
862.74000 g/mol
Structure
Chemical structure of sennoside A
Figure 1.1: Chemical structure of sennoside A

Sources

In summary, the chemical sennoside A has been analyzed from following sources:

Note that an analysis result in the database may indicate either presence or lack thereof of a chemical in an analyzed sample.

References

  1. L. Gao, T. Guo, X. Xu, and J. Yang, "Rapid identification and simultaneous analysis of multiple constituents from Rheum tanguticum Maxim. ex Balf. By UPLC/Q-TOF-MS.," Natural Product Research , vol. 31 , no. 13 , pp. 1529–1535 , DOI: 10.1080/14786419.2017.1280491 .

Analysis results

Analysis result 1

Detection technique Values Units
UV/Vis 270
350
nm
[M⁻ H]⁻ 861.19090 m/z
MS²⁻ 269.04490
283.02660
431.09830
699.13130
m/z
STD
False
TLC
False
UV/Vis detector description
UPLC-UV/Vis
Mass spectrometer description
UPLC-QTOF-ESI-MS/MS, HDMS
Organism
Rheum tanguticum  Maxim. ex Balf
wild
dried, powdered
Collection dates
2007-10
Sample note
The root samples were identified by Prof. Zhichuan Bai at the College of Horticulture and Landscape, Southwest University. Voucher specimens (No. 200712) were deposited at the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Extraction solvents
methanol
Extraction mass/volume-ratio
40 mg/mL
Extraction repeats
3
Extraction time
1 h 30 min
Extraction temperature
20±5 °C
Analysis solvents
methanol
Detection note
861.1909 and the loss of a glucoside unit (162.0523 Da) produced 699.1313.
References

L. Gao, T. Guo, X. Xu, and J. Yang, "Rapid identification and simultaneous analysis of multiple constituents from Rheum tanguticum Maxim. ex Balf. By UPLC/Q-TOF-MS.," Natural Product Research , vol. 31 , no. 13 , pp. 1529–1535 , DOI: 10.1080/14786419.2017.1280491 .